British Airways is launching flights to San Sebastian from London City Airport in summer 2020.
When the twice-weekly service starts in July, it will be the fifth Spanish route operated by BA from the Docklands airport.
Rachel Riley, head of commercial for BA at London City said: “The launch of this new route from London City will prove very popular with our leisure customers looking for new places to explore. It will be the first time San Sebastian is served from London City and we are excited to offer our customers another easy getaway leaving from the heart of London.”
British Airways is making further changes to its schedule from London City next summer with additional flights to Berlin, Florence, Glasgow, Manchester and Nice.
There will be some frequency reductions to Geneva, Ibiza and Rotterdam.
The airline is also launching a new summer-only service from Glasgow to Palma and adding an extra weekly flight from Stansted to Florence.